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And it works by several means'producing its anti-inflammatory effects via suppressing the activity of cyclooxygenase (COX), an enzyme which is responsible for the production of pro-inflammatory mediators such as the prostaglandins and topically, as a beta-hydroxy acid (and unlike alpha-hydroxy acids) salicylic acid is capable of penetrating and breaking-down fats and lipids. Keratosis Pilaris occurs when the pores and skin metabolizes and there is too significantly production of a distinct protein named keratin. So it's extremely important to be seen by a dermatologist to have those checked.