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In Reply to: ゴローズ posted by ybemueph on May 24, 19113 at 21:19:45:
In these two studies, scientists from MIT (Massachusetts Institute of Technology) focused on the H7N9 and H5N1 flu strains. They said their findings should help public health officials monitor how the viruses evolve, regarding their potential for human-to-human transmission. Senior author of the two papers published in Cell this week, Ram Sasisekharan, the Alfred H. Caspary Professor of Biological Engineering, believes their findings could also help guide the development of new vaccines. Influenza viruses are classified according to the type of HA (hemagglutinin) protein they contain. Humans are most commonly infected by the H1 and H3 proteins.
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The human immune system is not naturally prepared to fight off other HA types, and some of these other types can eventually evolve to attack human respiratory cells. Sasisekharan and team wanted to determine H7N9's and H5N1's ability to infect humans and transmit from human-to-human. Sasisekharan had already demonstrated in previous studies that an influenza virus' ability to infect humans depends on its HA protein. The protein binds to glycan (sugar) receptors that exist on the surface of respiratory cells.
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